For example isotopic water. 22 measurement of compartment volumes 221 the dilution principle.
![The Body Fluid Compartments The Body Fluids And Kidneys](https://doctorlib.info/physiology/textbook-medical-physiology/textbook-medical-physiology.files/image354.jpg)
The Body Fluid Compartments The Body Fluids And Kidneys
Measurement of body fluid compartment volumes. This volume is regulated by the movement of sodium. To measure extracellular water volume the ideal indicator should distribute rapidly and uniformly outside the cells and should not enter the cell compartment. A marker substance is selected whose physical characteristics are such that it distributes only in the body fluid compartment whose volume you wish to calculate. The compartment volume is calculated as. If the amount of the substance is known and the resulting concentration is measured the volume can be calculated. 222 total body water.
Body fluid compartments and measurement general physiology duration. The volume of a fluid compartment in the body can be measured by placing an indicator substance in the compartment allowing it to disperse evenly through out the compartments fluid and then analyzing the extent to which the substance becomes diluted. Compartment volumes are measured by determining the volume of distribution of a tracer. Extracellular fluid 27 189 litres. The fluid compartment volume. 3500 x 100.
The indicator dilution principle is based on the definition of a concentration. This is estimated by measuring the volume of distribution of isotopes of water. The everything else synovial fluid. Properties of the tracer and compartment measured blood volume versus plasma volume. Figure 254 shows this indicator dilution method of meas uring the volume of a fluid compartment which is based on the principle of conservation of mass. Total body water 30 012 ml d2o x 0001 ml d2oml water 29880 ml or 30 l therefore total body water as a percentage of body weight equals 50 in this woman.
This volume is regulated by the movement of free water. The extracellular fluid compartment volume. Measurement of body fluid compartments body fluid compartments can be measured by dilution of a compound that distributes only in the space of interest. Measurement of body fluid compartment volumes the volumes of body fluid compartments are measured with a method based on the principle of dilution. 100 38 5645 ml. Intracellular fluid 33 231 litres.
Compartment volumes are measured by determining the volume of distribution of a tracer substance. A known amount of a tracer is added to a compartment. If you know plasma volume and hematocrit of blood volume that is made up by cells total blood volume can be calculated. The tracer concentration in that compartment is measured after allowing sufficient time for uniform distribution throughout the compartment.